I am pretty sure that is absolutely, 100% bullshit because I can very obviously tell the difference between 22khz and 44khz, and I'm one of those guys who thinks audiophiles with 320kbps MP3s are crazy people.
Also "16-22 sounds like you'd expect from a Genesis styled game" is also total garbage. Let's do an experiment.
http://blaze.letsvideogame.com/TEMP/SoundTest.mp3
Tell me you can't hear the difference; this is a track from the official Sonic 2 OST. Not recorded from a VGM, not a GYM. This is directly from Sega.
You might be thinking of the SNES, which had a sampling rate limit of 32khz. But since a lot of the "signature sound" of the Sega Genesis is done through its FM Synth, the higher the bandwidth, the better.